References popup

The weeks shown in color represent the start and end points of chemical exposure for each study.

Study Results Study Details References

Results for Dioxin (TCDD)

Increased serum thyroid-stimulating hormone (TSH) with no change in T3 or T4

Subjects: Long-Evans rats

Chemical: Dioxin (TCDD)

Low doses tested: 1.0 μg/kg

Route of administration: dissolved in corn oil and delivered through gavage

Exposure duration: post-natal day 3 – single dose (comparable to human prenatal development from approximately day 1 of week 22 to day 1 of week 23)

Age of measurement: 25 days of age

Reference [PubMed Link]
Fenton SE, Hamm JT, Birnbaum LS, Youngblood GL. 2002. Persistent abnormalities in the rat mammary gland following gestational and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Toxicol Sci 67(1):63-74.